By focusing on the health of future mothers and their eggs before conception, the Female Fertility Research Program at the C.S. Mott Center for Human Growth and Development optimizes the resulting health of their children. We embrace the uniqueness of our local community and urban environment by providing an integrative “omics” approach to research- a rapidly evolving, multi-disciplinary, and emerging field that encompasses genomics, epigenomics, transcriptomics, proteomics, and metabolomics. The program’s ultimate goal is to improve couples’ reproductive success through personalized approaches to reproductive health, with equal emphasis on both partners. This leads to better health and fertility potential, and improved pregnancy outcomes that fulfill our mission to transform children’s health globally, starting in Detroit.