The overall long term goals of the lab are five fold:
- Mechanism discovery: to investigate the interaction between mayternal and fetal organ systems as it relates to pregnancy-adaptations in the etiology of gestational and early life disorders;
- Biomarker discovery: to develop state of the art non-invasive biomarkers and signature profiles during gestation both in healthy and pathophysiologic states;
- Therapeutic discovery: to predict, propose, and develop nutritional and pharmacologic therapeutic strategies that will have a practical clinical potential to prevent and/or ameliorate adverse pregnancy pathologies and developmental adaptations;
- Fetal programing of adult-onset diseases: to investigate fetal programing of adult-onset disease states;
- Strategic improvement of quality of life: to discover means to enhance the developmental environment that may have enduring and life-long health benefits for the offspring.
Dr. Jay Ramadoss is a professor in Obstetrics & Gynecology, Physiology and the C.S. Mott Center. He received his bachelors degree and masters degree in electronics and instrumentation engineering and chemistry, respectively, from BITS, Pilani in India, and his doctoral degree in biomedical sciences with an emphasis in fetal physiology from Texas A&M University. He performed postdoctoral studies in the area of reproductive physiology at the University of Wisconsin, Madison, Department of Obstetrics and Gynecology. He is a member of the Research Society on Alcoholism, the Fetal Alcohol Spectrum Disorders Study Group, the Society for Reproductive Investigation and the Perinatal Research Honor Society.
Dr. Ramadoss has served on over 20 National Institutes of Health Study Sections, as a reviewer for 22 peer-reviewed journals, and serves as an editorial board member/editor of select journals/special issues in his field. Widely published, he has secured numerous research grants and academic awards.
Through its lab members, the Ramadoss Lab is a steering force in generating knowledge in perinatology and novel physiologic approaches that improve pregnant women and children’s health through the innovation of basic and translational medical science.
The mission of the Ramadoss lab has its base in that of C. S. Mott Center at Wayne State University School of Medicine. Thus, as a research lab our unique mission is to:
- Discover etiologies underlying gestational disorders
- Develop empowering technologies for diagnosis and development of biomarkers
- Generate new knowledge that will improve pregnant women’s and children’s health with preventive and ameliorative strategies
Engaging driven and talented researchers, the lab operates closely with basic science and clinical researchers to understand critical problems in obstetric medicine and solve them using our scientific expertise.