At the C.S. Mott Center for Human Growth and Development, we know that education begins in the womb. When compared to other local and global regions, Detroit’s environmental factors, including pollution, genetics, race and socioeconomic stressors, all disproportionately affect fetal developmental programming in the city’s population. These stressors not only create distinct developmental consequences that impact both mother’s and children’s health and well-being, but also perpetuate transgenerational disease conditions.
The C.S. Mott Center’s Pregnancy and Neonatology Research Program examines metabolic and environmental factors, both external and internal, that impact the fetal developmental programming of adult disease. We aim to halt this perpetuating cycle of transgenerational disease progression that initiates in utero through the development of therapies that target and prevent abnormal outcomes.